Letting more time pass can be helpful
From a site perspective there is nothing wrong with posting multiple related questions together. Oblivious Sage's guidelines are a good reference point for the etiquette of doing so to avoid frustrating other users, but that certainly isn't a policy.
I think there is another factor to consider in posting related questions. How truly related your questions are will impact how useful this advice is. The more related the more relevant it will be.
If you are asking a related question then the answers and advice given on the early questions may impact how you ask about the later ones. This applies to both what you are asking and how you ask it.
Consider the case where you want to ask about a group of spells from the same source. Likely you would use a similar question format and structure. Potentially something in this format is unclear or confusing. If you ask all of the questions in a quick-fire manner you will then need to go and edit each one individually. It also creates more work for reviewers and commenters trying to help you. Alternatively, if you had only posted one question and waited before asking the next that revision process would already be complete and the second version of the question may not need as much work.
Also think about overlapping answers to your questions. It is entirely possible that an excellent answer to your first question may also answer, or partly answer your second question. That may impact how (or even if) you ask the second one.
Don't take this as a policy or advice against asking multiple questions. Instead when you want to ask multiple just take a second to think if the answer and comments on one of them could impact how you approach the second one. If so it may be worth waiting some time before asking.